Transfusion Science Webinar

Issues in ABO Antibody Titration

Webinar Illustration
Speaker image

Dr. Meenu Bajpai, MD Professor of Transfusion Medicine at the Institute of Liver and Biliary Sciences in New Delhi

Apr 29
Thu 10:30 AM CEST/01:30 AM PDT/4:30 PM SGT

Antibody titration is used to determine the concentration of a specific antibody and is a critical factor in various clinical settings. However, antibody titration is generally known as an “inherently imprecise procedure,” so automating this procedure is an important step towards better standardization, higher accuracy, and full traceability.

ABO antibody titration is used to support the decision of an ABO incompatible (ABOi) solid organ transplant. The titration result may influence decisions regarding acceptance of patients to the ABOi transplant program and suitability for transplant. Therefore, using a standardized and accurate method is key to avoid major clinical implications such as a risk of rejection or the exclusion from the ABOi transplant program.

In this webinar, Dr. Meenu Bajpai, MD, will share with us the main challenges in ABO Antibody Titration. She will walk us through the characteristics of ABO antibodies, the methods in use for the determination of ABO antibody titer, and the clinical applications of such a determination. She will also touch upon the automation of ABO titration for the gel method on the IH-500 system with all its benefits.

Speaker Name

Dr. Meenu Bajpai, MD
Professor of Transfusion Medicine at the Institute of Liver and Biliary Sciences in New Delhi

Dr. Meenu Bajpai, MD, is a professor of transfusion medicine at the Institute of Liver and Biliary Sciences, in Vasant Kunj, New Delhi. She has been working for the institute since 2008 where she has been involved in all administrative and academic activities related to transfusion medicine. Prior to joining the Institute of Liver and Biliary Sciences in 2008, she was the senior research associate in the department of transfusion medicine at All India Institute of Medical Sciences in New Delhi where she conducted a research project on the incidence of irregular antibodies other than anti-D in neonates with haemolytic disease of newborns. From 2004 and 2007, she was the senior resident in transfusion medicine for the Department of Transfusion Medicine at the Postgraduate Institute of Medical Education and Research in Chandigarh. She has been giving lectures in transfusion medicine for several years at various institutions in India and in 2009, she attended trainings in advanced blood group serology at the International Blood Group Reference Laboratory in Bristol, UK. She received several awards including the Princess of Wales Scholarship in Transfusion Medicine in 2009 from the British Blood Transfusion Society, Manchester, UK as well as the Harold Gunson Fellowship in Transfusion Medicine at the ISBT in Lisbon Portugal in 2011. She has authored more than 30 publications as well as chapters in transfusion medicine test books. She is currently the principal investigator of projects on the efficacy of convalescent plasma therapy in COVID-19 patients.