Whether your targets are proteins, nucleic acids, lipids, or carbohydrates we provide personalizable solutions to assist in the identification, characterization, and validation of your target molecules.
This fully integrated, semi-automated quantitative PCR workflow combines experimentally validated PrimePCR Pathway Plates and automated plate handling and data collection to reduce hands-on time by 50% and the time spent in the laboratory by 78%.
Our products and workflows for lead discovery and optimization include cell analysis and gene expression solutions as well as chromatography automation for high-throughput purifications.
Traditional sequential chromatography requires extensive user intervention, which is time-consuming and can affect reproducibility. We compare mAb purification using traditional sequential chromatography to automated purification on the NGC Chromatography System.
Our portfolio for preclinical studies includes multiplex immunoassays for multiple targets and applications, including safety and toxicity monitoring, and a large antibody portfolio, with anti-idiotypic and custom ADA generation services, for use across multiple applications.
Dr. Achim Knappik discusses Bio-Rad’s portfolio of anti-idiotypic antibodies and our ability to generate custom ADAs using proprietary HuCAL® recombinant antibody generation technology. The presentation concludes with a case study of the development of anti-trastuzumab antibodies.
We offer a range of solutions for clinical research, including critical raw materials and controls for clinical diagnostics, custom and off-the-shelf antidrug antibodies, autoimmune kits and instruments for in vitro diagnostics, and protein analysis and quantitation tools.
This review highlights challenges in antibody assay development, special considerations for PK and IR assays for monoclonal antibody drugs, and advances in genetic engineering that allow faster optimization and more specific assays.
Our solutions for design and optimization of production scale-up include automated chromatography systems, real-time PCR systems with high-throughput automation, and a wide range of protein analysis, quantitation, and identification tools with IQ/OQ and CFR-compliant software.
CHT Ceramic Hydroxyapatite is a leading purification medium in the downstream process industry. This guide provides an introduction to CHT and includes recommendations for activities ranging from method scouting and optimization to column packing.
Our manufacturing and QC testing solutions range from process-scale chromatography resins to the market-leading digital PCR system and reagents for residual host cell DNA quantification.