Support your Cryo‑EM analysis with a purification workflow that provides mono disperse protein samples for downstream cryo‑analysis.
In this article, you will learn how
- To achieve high resolution and low‑volume size exclusion chromatography (SEC) separations
- Simple tubing adaptations on the Bio‑Rad NGC Chromatography System enable the use of high‑resolution size exclusion columns for Cryo‑EM applications
- These adaptations allow for purification strategies using 8 µl fraction drops with a total delay volume of less than 45 µl
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