What is WBE and why is ddPCR technology such a good fit?
In recent years, public health officials have affirmed the need for robust methods capable of proactive detection of pathogens to alert to outbreaks and limit spread of disease. Longitudinal trend studies using wastewater-based epidemiology (WBE) and Droplet Digital™ PCR (ddPCR™) have been shown to be effective tools for these applications.
Advantages of WBE:
- Provides community-wide temporal trends
- Near real-time data, depending on the analysis method
- Passive sample collection that does not require individual participation approval
Advantages of ddPCR technology for WBE monitoring:
- Fast analysis time
- Absolute quantification
- Sensitive enough to detect low copy numbers
- Tolerant to PCR inhibitors that are present in wastewater
Wastewater-based epidemiology (WBE) and ddPCR technology are being used to address a broad set of health challenges, including SARS-CoV-2 (COVID), hMPXV, Influenza and RSV.
Influenza and RSVInfluenza and Respiratory syncytial virus (RSV) are extremely common human pathogens known to induce severe respiratory illness in infants, young children, or the elderly. Learn more about these WBE applications from the resources below.
Read the whitepaper: Population-Level Trending of Seasonal Respiratory Viruses with Droplet Digital PCR–Based Quantification in Wastewater
hMPXV (Human Monkeypox)Outbreaks of human monkeypox, caused by the hMPXV virus, are a relatively new concern. WBE and ddPCR technology are also being applied to this application. Learn more below.
Read the whitepaper: Proactive Community Detection of the Human Monkeypox Virus with Droplet Digital™ PCR and Wastewater-Based Epidemiology