You may encounter hemoglobin variant cases that require expertise to understand. Bio-Rad is here to help. To complement our world class hemoglobin testing systems, we offer educational support to help you serve the clinicians and patients who count on you.
Check out the various resources below!
Hemoglobinopathy Educational Program
Are you looking for tools to help you evaluate unusual chromatograms? Check out our Test Your Knowledge series of educational case studies. Each case study is designed to help you build and grow your knowledge and understanding of chromatograms.
Library of Variants Demo Video
Before jumping into the case studies, you might want to view our step-by-step video on how the Library of Variants tool can help you evaluate your chromatograms.
HbA1c Case Studies
Join us to understand different hemoglobin A1c testing methods and how hemoglobinopathies affect HbA1c results.
Marco Flamini reviews homozygous and double heterozygous hemoglobinopathies and their effects on HbA1c results.
Marco Flamini reviews cases of elevated HbF and the impact it has on various HbA1c testing methods.
Join us to understand different hemoglobin A1c testing methods and how hemoglobinopathies affect HbA1c results.
Case 1
Marco Flamini reviews a chromatogram showing an unknown peak just after HbA2.
A New Perspective on HbA1c Evaluation
By M. Flamini, MSc as seen in the Medical Laboratory Observer
Knowledge and awareness of thalassemia and hemoglobin variants affecting HbA1c measurements is essential. In this article, Marco Flamini emphasizes the need to evaluate hemoglobin variants that are coinherited with thalassemia and/or associated with elevated HbF. Ultimately, identifying the clinical status of the patient will lead to accurate result interpretation and better patient treatment decisions.
View the article today.
Thank you for your interest!
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Hemoglobinopathy Case Studies
To help you better evaluate thalassemia cases, we have selected two confirmed case studies from the Library of Variants for discussion. Click on each of the videos to learn and test your knowledge!
Case 1
Marco Flamini reviews one of the most typical chromatograms found in a hemoglobinopathy lab.
Case 2
Marco Flamini presents an unusual chromatogram and the steps for how to evaluate it.
To help you better evaluate sickle cell cases, we have selected confirmed sickle case studies from the Library of Variants for discussion. Click on the video to learn and test your knowledge.
Case 1
Marco Flamini reviews chromatograms for two sickle cell phenotypes.
To help you better evaluate hemoglobin variant cases, we have selected a confirmed case study from the Library of Variants for discussion. Click on the video to learn and test your knowledge!
Case 1
Marco Flamini reviews a chromatogram showing an unknown peak just after HbA2.
List of Hemoglobin Variants
Patient care is at the heart of what you do. We're here to help you serve clinicians and their patients. There are thousands of rare hemoglobin variants that could appear on your chromatograms. And since we know how important it is to identify unknown peaks and accurately analyze chromatograms, we've developed a list of hemoglobin variants that were run on the VARIANT II Beta Thalassemia Short Program.
This convenient list, organized by retention time, can be used as an educational tool to help when you are evaluating unfamiliar hemoglobin variant cases and considering further studies.
View the brochure today.
Thank you for your interest!
Download brochureWebinar: Evaluation of Hemoglobinopathies by HPLC
For more details on how to evaluate hemoglobinopathies by HPLC, register for our webinar.
Register now
Other Resource Tools to Guide Evaluations
Bio-Rad World of Hemoglobinopathies Map
We have developed several posters featuring common phenotypes that you can download, print, and hang in your laboratory to use as a quick reference. There are five different posters organized by the program you run and the region in which you operate.
Data collected from running the VARIANT II Beta-Thalassemia Short Program:
Bio-Rad World of Hemoglobinopathies Map
Download brochureBio-Rad World of Hemoglobinopathies Map: Common Mediterranean Phenotypes
Download brochureBio-Rad World of Hemoglobinopathies Map: Common Southeast Asian Phenotypes
Download brochureData collected from running the D-10 Dual Program:
Bio-Rad World of Hemoglobinopathies Map: Common Phenotypes Run on the D-10 Dual Program in a French Laboratory (English)
Download brochureBio-Rad World of Hemoglobinopathies Map: Common Phenotypes Run on the D-10 Dual Program in a French Laboratory (French)
Download brochureExpertise and Education
Hemoglobin Testing Solutions
DISCLAIMER
The purpose of this page, the educational videos, and the Library of Variants is to aid healthcare professionals with the interpretation of hemoglobin variant chromatograms and to suggest further studies for the final identification of the hemoglobin variant. All digital information contained on this page is for general information and educational purposes only. It is not intended to be, and should not be relied on as, a source of medical advice, and it should not be used to recommend a specific method of treatment or to diagnose a medical condition. Users should consult with appropriately trained healthcare professionals for medical advice, including diagnosis and treatment. Bio-Rad and all others (collectively, “Providers”) who have provided information to this page make no representations or warranties of any kind, including with respect to the accuracy or completeness of the information provided. Providers specifically disclaim all express or implied warranties of any kind, including, without limitation, any warranty of fitness for a particular purpose. No Provider shall be liable to any person or entity for any damages arising from the use of any information contained on this page in any form or under any legal theory whatsoever. In light of continuing regulations, developments, and advancements in the field of scientific research, users are strongly urged to review and independently evaluate the information contained on this page, and to consider, among other things, any changes in the instructions or added warnings and precautions that may be necessary. Bio-Rad has validated the retention times for HbS, HbC, HbD, HbE, HbF and HbA2 as described in the VARIANT II Beta-Thalassemia Short Program Instructions for Use. The content on this page is for informational purposes only and is not intended to provide medical advice or diagnosis.