Selecting optimal resins for process-scale mAb purification.
Selecting optimal resins for process-scale polyclonal antibody purification.
A three-step nonaffinity workflow that effectively delivers highly purified monoclonal antibodies.
A comparative study using apatite-based media to deliver highly purified chimeric IgG.
A simple and scalable process for separating Fab and Fc fragments using apatite-based media.
Characterized by high physical and chemical stability and unparalleled selectivity and resolution.
Delivers high recovery and versatility in large-scale purifications of difficult-to-purify proteins.
Provides exceptional resolution and high recovery and is ideal for intermediate and final polish applications.
Provides high binding capacity and resolution and delivers excellent performance for polishing applications.
Enables efficient capture of biopharmaceutical molecules from crude feedstreams.
Exceptional performance characteristics make Nuvia S ideal for a wide range of downstream processes.
Designed for the process-scale purification of monocolonal and polyclonal antibodies.
Delivers high productivity in the capture step through efficient capture of molecules of interest from crude feedstreams.
Provides high selectivity under demanding low pH conditions.
High dynamic binding capacity and exceptional flow properties allow processing of large sample volumes in short times.
A monoclonal antibody purification strategy with an affinity-based capture step using UNOsphere SUPrA™ Resin.
A non-affinity monoclonal antibody purification strategy with a cation exchange-based capture step using Nuvia S Resin.
Technical features of and data from Bio‑Rad resins ideal for the capture step of monoclonal antibody purifications.
Technical features of and data from Bio‑Rad resins ideal for the intermediate step of monoclonal antibody purifications.
Technical features of and data from Bio‑Rad resins ideal for the polish step of monoclonal antibody purifications.
See how ion exchange and mixed-mode resins can be used for non-IgG purification.
See how we achieved reduction of aggregate levels from ~34% to ~3% and increase in the monomer content to >96% using CHT XT during acidic mAb purification.
Nuvia HP-Q tailored to large biomolecule purification.