Method recommendations ranging from method scouting and optimization to column packing techniques.
Two-step process leading to adenovirus preparation with high yield and very low HCP and DNA contamination.
Comparison of various mixed-mode media to determine the optimal choice for an efficient purification process.
A simple and reproducible process resulting in a concentrated preparation of highly pure and active virus.
A comparative study using apatite-based media to deliver highly purified chimeric IgG.
Simplify the process of antibody purification using a strong cation exchanger and ceramic hydroxyapatite.
A simple and scalable process for separating Fab and Fc fragments using apatite-based media.
An effective and simple process for aggregate removal from IgG products using CHT™ Ceramic Hydroxyapatite.
Quantifying the total calcium concentration in the effluent of a CHT Ceramic Hydroxyapatite packed bed.
Tips and tricks to achieve the best packing results for CHT Media.
Three-step nonaffinity workflow that effectively delivers highly purified mAbs with minimal feed conditioning.
Find out how CHT interacts chemically with different biomolecules by affinity, CEX, or mixed-mode interactions.
Find the optimal buffers and guidelines for method development with CHT.
See how scalable and easy CHT column packing is with this five-step protocol.
Learn about purification of influenza and dengue viruses using CHT XT to get >75% recovery and >90% reduction in contaminating proteins.
See how we achieved reduction of aggregate levels from ~34% to ~3% and increase in the monomer content to >96% using CHT XT during acidic mAb purification.
Learn how Nuvia cPrime Mixed-Mode Resin can purify an active enzyme with ~96% purity in a single step.