Unlocking the Potential of Bispecifics, GPCR Antibodies, and Lead Generation
Learn how to accelerate antibody discovery with Pioneer™ Antibody Discovery Platform
Identifying functional lead candidates is a critical step in biologics R&D and the foundation for building innovative therapeutic pipelines. The process can be slowed by challenges such as generating binders to complex targets like transmembrane proteins, immunosuppressive molecules, or pH-sensitive antigens.
The Pioneer Antibody Discovery Platform was engineered to overcome these obstacles. Combining a large, developable, and highly diverse Fab library with our proprietary SpyDisplay™ technology, the Platform enables rapid discovery of high-affinity, functional antibodies against difficult targets.
In this webinar exclusively for Takeda, we’ll introduce the sophisticated design of the Pioneer Platform, highlight how SpyDisplay—based on SpyTag technology—enables efficient selection, and present data from successful antibody campaigns against TIGIT, IL-6R, C5aR, and CXCR4. These case studies showcase the generation of diverse, functional leads that perform comparably or better than clinically developed antibodies.
You will learn:
- The design and capabilities of the Pioneer Library, one of the largest functional human Fab libraries
- How SpyDisplay™ technology enables high-affinity selection
- How TrailBlazer™, our modular antibody assembly system, allows for fast and easy screening in a variety of formats
- Case studies on antibody discovery against TIGIT, IL-6R, C5aR, and CXCR4
- How SpyLock technology enables generation of bispecific antibodies for high-throughput screening
Paul Royle, PhD,
Market Development Manager, Bio-Rad
Paul Royle is the Market Development Manager for Bio-Rad’s Custom Antibody Service and has been with Bio-Rad’s Antibody Division for 12 years. Prior to this, he worked in an immunology diagnostics company for almost 7 years. Paul holds a degree and PhD from the University of Nottingham, UK, and has post-doctoral research experience from the University of Warwick, UK.